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Publicatielijst 2019

  • Important work on the definitions for Transfusion-associated circulatory overload (TACO) and Transfusion-associated acute lung injury (TRALI)
    Wiersum-Osselton JC, Whitaker B, Grey S, et al. Revised international surveillance case definition of Transfusion-associated circulatory overload (TACO): a classification agreement validation study. Lancet Haematology 2019; forthcoming
    Bolton-Maggs PHB (Ed), Poles D, Watt A, Thomas D and Cohen H on behalf of the Serious Hazards of Transfusion (SHOT) Steering Group. The 2012 Annual SHOT Report (2013) https://www.shotuk.org/wp-content/uploads/myimages/SHOT-Annual-Report-20121.pdf
    Vlaar APJ, Toy P, Fung M, et al. A consensus redefinition of transfusion-related acute lung injury. Transfusion. 2019 Apr 16. doi: 10.1111/trf.15311. [Epub ahead of print]
  • International haemovigilance: what have we learned and what do we need to do next?
    E.M.Wood, A. L. Ang, A. Bisht, P. H. Bolton-Maggs, A. G. Bokhorst, O. Flesland, K. Land, J.C. Wiersum-Osselton, M.R. Schipperus, P. Tiberghien, B.I. Whitaker
    Transfusion Medicine Reviews 2019 doi: 10.1111/tme.12582
  • Can we prevent vasovagal reactions in young inexperienced whole blood donors? A placebo controlled study comparing effects of a 330 vs 500 ml water drink prior to donation
    Johanna Wiersum-Osselton , Bas Romeijn, Elise van den Brekel, Anne van Dongen, Frank Hermans, Arlinke Bokhorst and Tanneke Marijt-van der Kreek. Transfusion. 2019 Feb;59(2):555-565. doi: 10.1111/trf.15065

Publicatielijst 2018

  • Comparing transfusion reaction risks for various plasma products – an analysis of 7 years of ISTARE haemovigilance data
    Nicholas H. Saadah,1,2 Johanna G. van der Bom,1,2 Johanna C. Wiersum-Osselton,3,4,5 Clive Richardson,5,6 Rutger A. Middelburg,1,2 Constantina Politis,5,7 Philippe Renaudier,5,8 Pierre Robillard5,9 and Martin R. Schipperus4,10, British Journal of Haematology 2018, doi: 10.1111/bjh.15082
  • Prioritizing of bacterial infections transmitted through substances of human origin in Europe
    Dragoslav Domanovic, Alessandro Cassini,Isabelle Bekeredjian-Ding, Arlinke Bokhorst, Martijn Bouwknegt,Giuseppina Facco,George Galea, Paolo Grossi, Ramadan Jashari, Christoph Jungbauer, Jan Marcelis, Ioana Raluca-Siska, Inger Andersson-Vonrosen, and Jonathan E. Suk
  • TACO: een complicatie van bloedtransfusies
    Dr. A.W.M.M. Koopman-van Gemert, Dr. E.G. Mik, A.J.W. van Tilborgh- de Jong, P. van der Valk, Dr. A.J.P. Vlaar, Dr. J.C. Wiersum-Osselton A&I, no.1, maart 2018
  • Transfusion reactions after transfusion of platelets stored in PAS-B, PAS-C, or plasma: a nationwide comparison
     Fabienne M.A. van Hout ,1,2 Pieter F. van der Meer ,1 Johanna C. Wiersum-Osselton,3 Rutger A. Middelburg ,1,2 Martin R. Schipperus,3,4 Johanna G. van der Bom,1,2 and Jean-Louis Kerkhoffs1,4 TRANSFUSION 2018 Apr;58(4):1021-1027
  • Direct costs of transfusion reactions – an expert judgement approach
     Janssen MP, van Tilborgh AJW, de Vooght KMK, Bokhorst AG, Wiersum-Osselton JC. Vox Sang. 2018 Feb;113(2):143-151
  • International validation of harmonized definitions for complications of blood donations
     Kevin J. Land, Mary Townsend, Mindy Goldman, Barbee I. Whitaker, Gabriela E. Perez and Jo C. Wiersum-Osselton. TRANSFUSION 2018 Nov;58(11):2589-2595
  • Patient blood management in colorectal cancer patients: a survey among Dutch gastroenterologists, surgeons, and anesthesiologists
     Michael J. Wilson, Ankie W.M.M. Koopman‐van Gemert, Joris J. Harlaar, Johannes Jeekel, Jaap Jan Zwaginga, Martin Schipperus. Transfusion, 10 September 2018
  • Short-term effect of preoperative intravenous iron therapy in colorectal cancer patients with anemia: results of a cohort study
    M.J. Wilson, J.W. Dekker, E. Bruns, W. Borstlap, J. Jeekel, J.J. Zwaginga, M.R. Schipperus Transfusion. 2018 Mar;58(3):795-803
  • Iron therapy as treatment of anemia: A potentially detrimental and hazardous strategy in colorectal cancer patients
     M.J. Wilson, J.J. Harlaarc, J. Jeekel, M. Schipperus, J.J. Zwaginga Med Hypotheses. 2018 Jan;110:110-113

Proefschrift

Proefschrift Michael J. Wilson (gepromoveerd op 18 december 2018 te Leiden), Preoperative blood management in colorectal cancer surgery: the controversial role of iron

Proefschrift Nicholas H. Saadah (gepromoveerd op 11 september 2018 te Leiden), Hemovigilance, heterogeneity, and hyperfibrinolysis

Gerelateerde publicatie

Kwaliteitsopdracht adviesrapport: Het bewaren van erytrocyten- en trombocytentransfusiezakken in het EKZ (Amsterdam UMC)
Floor Groeneveld, Kinderverpleegkundige in opleiding, Amsterdam UMC

Eerdere publicaties
Eerdere publicaties

Publicatielijst 2017

  • Transfusion reactions after transfusion of platelets stored in PAS-B, PAS-C, or plasma: a nationwide comparison.
    van Hout FMA, van der Meer PF, Wiersum-Osselton JC, Middelburg RA, Schipperus MR, van der Bom JG, Kerkhoffs JL.
    Transfusion. 2018 Feb 6. doi: 10.1111/trf.14509. [Epub ahead of print]
  • Comparing transfusion reaction risks for various plasma products – an analysis of 7 years of ISTARE haemovigilance data.
    Saadah NH, van der Bom JG, Wiersum-Osselton JC, Richardson C, Middelburg RA, Politis C, Renaudier P, Robillard P, Schipperus MR.
    Br J Haematol. 2018 Mar;180(5):727-734. doi: 10.1111/bjh.15082. Epub 2018 Jan 9.
  • Storage medium of platelet transfusions and the risk of transfusion-transmitted bacterial infections.
    Kreuger AL, Middelburg RA, Kerkhoffs JH, Schipperus MR, Wiersum-Osselton JC, van der Bom JG.
    Transfusion. 2017 Mar;57(3):657-660. doi: 10.1111/trf.13969. Epub 2017 Jan 31.
  • Effect of solvent/detergent-treated pooled plasma on fibrinolysis in reconstituted whole blood
     Nicholas H. Saadah, Pieter F. van der Meer, Herm Jan M. Brinkman, Dirk de Korte, Ido J. Bontekoe, Herbert H. Korsten, Rutger A. Middelburg, Johanna G. van der Bom and Martin R. Schipperus Transfusion. 2017 Sep;57(9):2104-2114. doi: 10.1111/trf.14245. Epub 2017 Aug 2.
  • Long term prognostic value of preoperative anemia in patients with colorectal cancer: a systematic review and meta-analysis
    M.J. Wilson, M. van Haaren, J.J. Harlaar, Hee Chul Park, H.J. Bonjer, J. Jeekel, J.J. Zwagina, M.R. Schipperus
    Surg Oncol. 2017 Mar;26(1):96-104. doi: 10.1016/j.suronc.2017.01.005. Epub 2017 Feb 2.
  • Comparing transfusion reaction rates for various plasma types: a systematic review and meta-analysis/regression
    Nicholas H. Saadah, Fabienne M.A. van Hout,3 Martin R. Schipperus, Saskia le Cessie, Rutger A. Middelburg, Johanna C. Wiersum-Osselton, and Johanna G. van der Bom
    Transfusion. 2017 Sep;57(9):2104-2114. doi: 10.1111/trf.14245. Epub 2017 Aug 2.
  • The role of preoperative iron deficiency in colorectal cancer patients: prevalence and treatment
    M.J. Wilson, J.W.T. Dekker, J.J. Harlaar, J. Jeekel, M.R. Schipperus, J.J. Zwaginga
    International Journal of Colorectal Disease, 2017 Nov;32(11):1617-1624. doi: 10.1007/s00384-017-2898-1. Epub 2017 Sep 9.
  • Direct costs of transfusion reactions – an expert judgement approach
    M.P. Janssen, A.J.W. van Tilborgh, K.M.K. de Vooght, A.G. Bokhorst, J.C. Wiersum-Osselton
    Vox Sanguinis, Vox Sang. 2018 Feb;113(2):143-151. doi: 10.1111/vox.12614. Epub 2017 Nov 9.
  • Prioritizing of bacterial infections transmitted through substances of human origin in Europe
    Dragoslav Domanovic, Alessandro Cassini,Isabelle Bekeredjian-Ding, Arlinke Bokhorst, Martijn Bouwknegt,Giuseppina Facco,George Galea, Paolo Grossi, Ramadan Jashari, Christoph Jungbauer, Jan Marcelis, Ioana Raluca-Siska, Inger Andersson-Vonrosen, and Jonathan E. Suk
    Transfusion. 2017 May;57(5):1311-1317. doi: 10.1111/trf.14036. Epub 2017 Feb 24.
  • Short-term effect of preoperative intravenous iron therapy in colorectal cancer patients with anemia: results of a cohort study
    M.J. Wilson, J.W. Dekker, E. Bruns, W. Borstlap, J. Jeekel, J.J.  Zwaginga, M.R. Schipperus
    Transfusion. 2018 Mar;58(3):795-803. doi: 10.1111/trf.14456. Epub 2017 Dec 17.
  • Iron therapy as treatment of anemia: A potentially detrimental and hazardous strategy in colorectal cancer patients
    M.J. Wilson, J.J. Harlaarc, J. Jeekel, M. Schipperus, J.J. Zwaginga
    Med Hypotheses. 2018 Jan;110:110-113. doi: 10.1016/j.mehy.2017.12.011. Epub 2017 Dec 5.
  • Short-term effect of preoperative intravenous iron therapy in colorectal cancer patients with anemia: results of a cohort study
    M.J. Wilson, J.W. Dekker, E. Bruns, W. Borstlap, J. Jeekel, J.J.  Zwaginga, M.R. Schipperus
    Transfusion, Volume 00, December 2017
  • Comparing transfusion reaction rates for various plasma types: a systematic review and meta-analysis/regression
    Nicholas H. Saadah, Fabienne M.A. van Hout,3 Martin R. Schipperus, Saskia le Cessie, Rutger A. Middelburg, Johanna C. Wiersum-Osselton, and Johanna

Publicatielijst 2016

  • Donors’ Health State the Year after Peripheral Haematopoietic Progenitor Cell Collection: A Prospective Follow-Up Study in Related and Unrelated Donors Compared to First-Time Platelet Donors.I. Bank, J.C. Wiersum-Osselton, S.M. Van Walraven, T. Netelenbos, M. Fechter, T. Marijt-van der Kreek, B.M.A.M. Bär, J.G. Van der Bom and A. Brand. J Clin Apher. 2016 Jan 27. doi: 10.1002/jca.21444. [Epub ahead of print]
  • CHAPTER 6: Donor vigilance and hemovigilance.Øystein Flesland & Johanna C. Wiersum-Osselton. Rossi’s Principles of Transfusion Medicine, Fifth Edition. Edited by Toby L. Simon, Jeffrey McCullough, Edward L. Snyder, Bjarte G. Solheim, and Ronald G. Strauss. 2016, John Wiley & Sons, Ltd. Pages 58-68. (in press)
  • The International Haemovigilance Network Database for the Surveillance of Adverse Reactions and Events in Donors and Recipients of Blood Components: technical issues and results.C. Politis, J. C. Wiersum, C. Richardson, P. Robillard, J. Jorgensen, P. Renaudier, J.-C. Faber & E. M. Wood. Vox Sanguinis (2016) DOI: 10.1111/vox.12447
  • Economic landscapes of human tissues and cells for clinical application in the EU.Final report EAHC/2012/Health/19TRIP, Rathenau Instituut, Foundation of European Tissue Banks

Publicatielijst 2015

  • Wrong blood in tube – potential for serious outcomes: can it be prevented?Paula H. B. Bolton-Maggs, Erica M. Wood and Johanna C. Wiersum-Osselton. Br J Haematol. 2015 Jan;168(1):3-13. doi: 10.1111/bjh.13137. Epub 2014
  • Development of standard definitions for surveillance of complications related to blood donation.Goldman M, Land K, Robillard P, Wiersum-Osselton J. Vox Sang. 2015 Sep 11. doi: 10.1111/vox.12323. [Epub ahead of print] PMID: 26361365
  • Presence of medication taken by blood donors in plasma for transfusionA. J. W. van Tilborgh-de Jong, J. C. Wiersum-Osselton, D. J. Touw & M. R. SchipperusVox Sanguinis Volume 108, no. 4, May 2015
  • Quality indicators for the hospital transfusion chain: a national survey conducted in 100 dutch hospitalsP.Y. Zijlker-Jansen, M.P. Janssen, A.J.W. van Tilborgh-de Jong, M.R. Schipperus, J.C. Wiersum-OsseltonVox Sanguinis Volume 109, no. 3, October 2015
  • International survey on definitions and current practices in prevention, diagnosis, management and reporting of transfusion-transmitted bacterial infectionsE. Chew, R.J. Benjamin, C.P. McDonald, J.C. Wiersum-Osselton, E.M. Wood  on behalf of the International Society of Blood Transfusion Working Parties on Transfusion-Transmitted Infectious Diseases (Bacterial subgroup) and Haemovigilance.ISBT Science Series 2015: 10(1), 31-40.
  • New perspectives for tissue banking in EuropeA. Bokhorst, Director TRIP Foundation, National Office for Hemo- and Biovigilance, The NetherlandsPostmortale Gewebespende: Quo Vadis, Jahresband 2014/15 – Stiftung Europäische Gewebebanken

Publicatielijst 2014

  • A.J.W. van Tilborgh-de Jong, J.C. Wiersum-Osselton, P.Y. Zijlker-JansenThe Prevention of Transfusion Associated Circulatory Overload, Tijdschrift voor Bloedtransfusie (2014; Nr. 1)
  • P.E.A. Huijts, J.C. Wiersum-Osselton, A.J.W. van Tilborgh-de Jong, P.Y. Zijlker-JansenTRIP-rapport 2012: bevindingen hemovigilantie, Tijdschrift voor Bloedtransfusie (2014; Nr. 1)

Proefschrift

  • Proefschrift J.C. Wiersum-Osselton (promotie 19 maart 2013)Hemovigilance: is it making a difference to safety in the transfusion chain?

Posters

Publicatielijst 2013

Publicatielijst 2012

  • J. C. Wiersum-Osselton, J. C. Faber, C. Politis, A. Brand, J. G. van der Bom, M. R. Schipperus. Quality validation of data in national haemovigilance systems in Europe: report of a survey on current state of practice Vox Sanguinis 2012, DOI: 10.1111/j.1423-0410.2012.01659.x
  • Schipperus MR, Wiersum-Osselton JC, Zijlker-Jansen PY, van Tilborgh-de Jong AJW. The Dutch Hemovigilance System: Transfusion Reactions In Patients (TRIP). In: de Vries RRP, Faber JC (eds) Hemovigilance: an effective tool for improving transfusion safety. 2012. ISBN 978-0-470-65527-6.
  • J.C. Wiersum-Osselton, W. de Kort, T. Marijt-van der Kreek, H.J.C. de WitSetting up or consolidating a system for donor hemovigilance at the level of a blood establishment. In: Hemovigilance: an effective tool for improving transfusion safety. Editors R.R.P. de Vries and J.C. Faber. 2012.ISBN 978-0-470-65527-6.
  • J.C. Wiersum-Osselton, A.J.W. van Tilborgh-de Jong, P.Y. Zijlker-Jansen, L.M.G. van de Watering, A. Brand, J.G. van der Bom, M.R. Schipperus. Variation between hospitals in rates of reported transfusion reactions: is a high reporting rate an indicator of safer transfusion? Vox Sanguinis (Epub ahead of print, DOI: 10.1111/j.1423-0410.2012.01642.x)
  • Middelburg RA, Beckers EA, Porcelijn L, Lardy N, Wiersum-Osselton JC, Schipperus MR, Vrielink H, Briët E, van der Bom JG. Allo-exposure status and leucocyte antibody positivity of blood donors show a similar relation with TRALI. Transfus Med. 2012 Apr;22(2):128-32. doi: 10.1111/j.1365-3148.2012.01140.x. Epub 2012 Mar 1. PMID: 22380759.
  • Reesink HW, Lee J, Keller A, Dennington P, Pink J, Holdsworth R, Schennach H, Goldman M, Petraszko T, Sun J, Meng Y, Qian K, Rehacek V, Turek P, Krusius T, Juvonen E, Tiberghien P, Legrand D, Semana G, Muller JY, Bux J, Reil A, Lin CK, Daly H, McSweeney E, Porretti L, Greppi N, Rebulla P, Okazaki H, Sánchez-Guerrero SA, Baptista-González HA, Martínez-Murillo C, Guerra-Márquez A, Rodriguez-Moyado H, Middelburg RA, Wiersum-Osselton JC, Brand A, van Tilburg C, Dinesh D, Dagger J, Dunn P, Brojer E, Letowska M, Maslanka K, Lachert E, Uhrynowska M, Zhiburt E, Palfi M, Berlin G, Frey BM, Puig Rovira L, Muñiz-Diaz E, Castro E, Chapman C, Green A, Massey E, Win N, Williamson L, Silliman CC, Chaffin DJ, Ambruso DR, Blumberg N, Tomasulo P, Land KJ, Norris PJ, Illoh OC, Davey RJ, Benjamin RJ, Eder AF, McLaughlin L, Kleinman S, Panzer S. Measures to prevent transfusion-related acute lung injury (TRALI). Vox Sang. 2012 Apr 20. doi: 10.1111/j.1423-0410.2012.01596.x. [Epub ahead of print] No abstract available. PMID: 22519920 .
  • Wiersum-Osselton JC, Marijt-van der Kreek T, de Kort WL. Donor vigilance: progress and challenges. ISBT Science series 2012, Volume 7:251-5.
  • Wiersum-Osselton JC, Marijt-van der Kreek T, de Kort WL. Donor vigilance: what are we doing about it? Biologicals. 2012 May;40(3):176-9. Epub 2012 Jan 9. PMID: 22230318.
  • Wiersum-Osselton JC, van Walraven SM, Bank I, Lenselink AM, Fibbe WE, van der Bom JG, Brand A. Clinical outcomes after peripheral blood stem cell donation by related donors: a Dutch single-center cohort study.Transfusion. 2012 May 3. doi: 10.1111/j.1537-2995.2012.03676.x. [Epub ahead of print] PMID: 22554279.
  • Middelburg RA, Borkent B, Jansen M, van de Watering LM, Wiersum-Osselton JC, Schipperus MR, Beckers EA, Briët E, van der Bom JG. Storage time of blood products and transfusion-related acute lung injury.Transfusion. 2012;52:658-67.

Publicatielijst 2011

  • P.Y. Zijlker-Jansen, J.C. Wiersum-Osselton, A.J.W. van Tilborgh-de Jongh, K. Spijker, I. Streefkerk, M.H. Beunis,Y. van Maaren, A. Rohrbach, A.W.M.M. Koopman-van Gemert, M.R. Schipperus.Eigen bloed altijd goed? Overzicht meldingen van bijwerkingen en incidenten bij bloedbesparende technieken aanTRIP Landelijk Hemovigilantie Bureau.Tijdschrift voor bloedtransfusie vol. 4, nr. 1-2011
  • J.C. Wiersum-Osselton, R.A. Middelburg, E.A.M. Beckers, A.J.W. van Tilborgh, P.Y. Zijlker-Jansen, A. Brand,J.G. van der Bom en M.R. Schipperus.Male-only fresh-frozen plasma for transfusion-related acute lung injury prevention: before-and-after comparativecohort study.Transfusion Volume 51, June 2011, blz. 1278-1283
  • Middelburg RA, van Stein D, Atsma F, Wiersum-Osselton JC, Porcelijn L, Beckers EA, Briët E, van der Bom JG. Alloexposed blood donors and transfusion-related acute lung injury: a case-referent study. Transfusion 2011;51(10):2111-7.

Publicatielijst 2010

  • K. Spijker, J.C. Wiersum-Osselton, M.R. Schipperus.De verschillende alternatieven voor quarantaine FFP. Tijdschrift voor bloedtransfusie vol. 3, nr. 4-2010
  • J.C. Wiersum, A.J.W. van Tilborgh-de Jong, P.Y. Zijlker-Jansen en M.R. Schipperus.Hemovigilantie: het TRIP rapport 2008. Tijdschrift voor bloedtransfusie vol.3 nr. 1-2010
  • Wiersum-Osselton JC, van Tilborgh AJ, Zijlker-Jansen PY, Mangundap KM, Schipperus MRReesink HW, Panzer S, Gonzalez CA, Lena N, Muntaabski P, Gimbatti S, Wood E, Lambermont M,Deneys V, Sondag D, Alport T, Towns D, Devine D, Turek P, Auvinen MK, Koski T, Lin CK, Lee CK,Tsoi WC, Lawlor E, Grazzini G, Piccinini V, Catalano L, Pupella S, Kato H, Takamoto S, Okazaki H,Hamaguchi I, , Dinesh D, Flanagan P, Flesland O, Steinsvåg CT, Espinosa A, Letowska M, Rosiek A,Antoniewicz-Papis J, Lachert E, Koh MB, Alcantara R, Corral Alonso M, Muñiz-Diaz E.Haemovigilance for the optimal use of blood products in the hospital.Vox Sang. 2010 Mar 21. [Epub ahead of print] No abstract available.PMID: 20345518 [PubMed – as supplied by publisher]Related articles

Publicatielijst 2009

Publicatielijst 2008

  • J.C. Wiersum-Osselton, A. van Tilborgh, P. Zijlker, M.R. Schipperus.TRIP over de grenzen: hemovigilantie en internationale samenwerkingTijdschrift voor Bloedtransfusie, jaargang 1, nr. 3, december 2008
  • J.C. Wiersum-Osselton, M.R. Schipperus, L. Porcelijn, D. van Stein, A.P.J. Vlaar, E.A.M. Beckers.Transfusion-Related Acute Lung Injury (TRALI) in Nederland in 2002-2005.Nederlands Tijdschrift voor Geneeskunde, jaargang 152, nr. 32 ,augustus 2008

Publicatielijst 2006

  • E.A.M. Beckers, M.R. Schipperus, P.A.W. te Boekhorst. Hemovigilantie, meer dan papier alleen
    Nederlands Tijdschrift voor Hematologie, jaargang 3, nr. 1 jan./febr. 2006

Publicatielijst 2005

  • M.R. Schipperus, J.C. Wiersum-Osselton.Transfusiebeleid in Nederland: het opzetten van een landelijk registratiesysteem voor transfusiereacties (TRIP)
    Patiëntveiligheid in Nederland, Verbeterinitiatieven en innovaties in de zorg, 2005: pg. 29
  • J.C. Wiersum-Osselton, M.R. Schipperus. Transfusiereacties bij patiënten: hemovigilantiemeldingen aan het Landelijk Hemovigilantiebureau over 2003
    Nederlands Tijdschrift Geneeskunde 2005 19 november; 149(47)

Publicatielijst 2004

  • J.C. Wiersum-Osselton, M.R. Schipperus, R.R.P. de Vries. Contribution to International Forum Transfusion Safety in the Hospital
    Vox Sanguinis 2004; 87: 48-62
  • J.C. Wiersum-Osselton, M.R. Schipperus. Hemovigilantie en TRIP meldingen: Praktijk en resultaat van het  eerste rapportagejaar
    NVB bulletin December 2004 nr. 4

Publicatielijst 2003

  • M.R. Schipperus, C.L. van der Poel. Veilige bloedtransfusie, Nederlands hemovigilantiesysteem van start
    Medisch Contact 58e jaargang, 7 maart 2003: pg. 392-393
  • C.L. van der Poel, M.R. Schipperus. The Emerging Dutch Hemovigilance System: Voluntary and State-of-the-Art
    TATM (Transfusion Alternatives in Transfusion Medicine) volume 5, nr. 1, april 2003: pg. 256-259
  • J.C. Wiersum-Osselton, M.R. Schipperus. Landelijk Hemovigilantie-systeem, Start Bureau TRIP (Transfusie Reacties in Patiënten)
    NVB bulletin oktober 2003 (3) 24-26